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Gloria Brame, Ph.D.

Acrux: Roll on a better libido (men)

Filed By Gloria Brame, Ph.D. | October 04, 2009 10:00 AM | comments

Filed in: Living
Tags: roll-on testosterone, sex and aging

A new testosterone treatment to restore libido in the aging male population may be coming to a pharmacy near you in the next year or two.  Australian company Acrux has announced trial results of its new drug, Axiron, which offers both a great delivery system (you apply it like roll-on deodorant in your armpits) and very promising results.  acrux.gifCurrently, transdermal testosterone delivery (using a gel) is messy and unpleasant for the user and his lovers.

It's good news for baby boomers.  According to Bloomberg news, "More than a third of American men over 45 years suffer testosterone deficiency, U.S. researchers found in a 2006 study. It can sap sex drive and cause impotence, osteoporosis and memory loss, according to the Mayo Clinic in Rochester, Minnesota.

Bloomberg estimates that Axiron could be BIG (as in VERY profitable to its manufacturer): "The global market for testosterone treatments was worth $1 billion in the year ended March and grew more than 20 percent in the U.S."

Not surprisingly, while Acrux has yet to make a profit, their shares have tripled in anticipation of this drug's market potential.

Here's the scientific scoop: Hopes Rise for Acrux Testosterone Treatment.

Acrux has developed a delivery mechanism for its testosterone treatment that is applied to the armpit using a device that is similar to a roll-on deodorant. Clothes can be put on immediately after application and there is little chance of transferring it to another person.

Patients in the Axiron trial reported improved mood, a fall in negative mood, increased sexual desire and increased sexual performance.

The FDA has agreed to Acrux submitting a new drug application in America with Acrux targeting submission by the end of 2009.


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Also a very useful supplement to FtoMs who need a little extra a few days before the next T-shot.

The problem even with intramuscular injections is that for the first few days after the injection, there's a bit too much, and a few days before the next shot, a bit too little.

Rather than merely restoring a flagging libido, this will cause measurable health benefits in terms of preventing osteoporosis etc.

Zoe, yes! Great point. Thanks for adding it.

Robert Ganshorn Robert Ganshorn | October 5, 2009 3:17 AM

I was diagnosed with this problem and upon coming to Thailand discovered that the Thais, free of the American pharma industry, determined that topical gels are irrelevant. They regard them as a rip off and will not even allow them into the country. I have taken an oral testosterone manufactured in the Netherlands by a company called Organon branded Andriol testocaps. I have had excellent results for two years now using these instead of a gel. It costs less than a quarter of the amount of the gel. I strongly recommend it to all if it does the job well for you.

Trans persons I have spoken with who use injections have also benefited by the consistent daily dose of supplement they receive.

It should be added that testosterone is important for muscle mass, energy level, well being, a calm mind and the ability to focus on problems. It is not just about memory loss.

I would encourage men to be certain to get their levels checked from age 50 onward (concurrent with prostate health monitoring) and be aware that "more is not better" as there is a heightened risk of prostate cancer with over supplementation.

How interesting. I automatically thought, "I'll bet this would really benefit a transman." Thanks Zoe!

Do they have something that rolls on that chills your libido out? My guy down there gets me into more trouble... ;-)

Robert Ganshorn Robert Ganshorn | October 5, 2009 10:41 AM

The concept is nice, your mom could roll it on before you left the house! :) but no. Also the degree of sexual desire and function is very individual. I had no difficulty with libido, but horrible fatigue.

Don't worry, there are still cold showers.